Plenary Session 5 - Towards Cartilage Repair

Designer Scaffolds for Cartilage Repair

Timeslot: Friday, April 28, 2017 - 10:45am to 11:15am

About

The search for replacement body parts has fuelled the highly interdisciplinary field of tissue engineering and regenerative medicine (1,2) as a treatment for the failure of one part of the body – the knees, for example. This talk will also describe our research on the design of new imaging approaches (3) and new materials to direct stem cell differentiation for regenerative medicine (4).

References:
[1] Stevens MM, George JH. Exploring and engineering the cell surface interface. Science 2005;310:1135-8.
[2] Reznikov N, Steele JAM, Fratzl P, Stevens MM. A materials science vision of extracellular matrix mineralization. Nature Reviews Materials 2016;DOI: 10.1038/natrevmats.2016.41.
[3] Autefage H, Gentleman, Littmann E, Hedegaard MAB, Von Erlach T, O'Donnell M, Burden FR, Winkler DA, Stevens MM. Sparse feature selection methods identify unexpected global cellular response to strontium-containing materials. Proceedings of the National Academy of Sciences of the United States of America 2015;112:4280-4285.
[4] Crowder SW, Leonardo V, Whittaker T, Papathanasiou P, Stevens MM. Material cues as potent regulators of epigenetics and stem cell function. Cell Stem Cell 2016;18:39-52.

Objectives